Suggestion - New Topics in 17th Harrison which are left out

[ayaskant12]

can i know from where u found that c-anca is positive in crescentic glomerulonephritis??

[Bruno]

from http://www.suite101.com/blog/daisyelain ... e_diseases

can i know from where u found that c-anca is positive in crescentic glomerulonephritis??

Perinuclear or P-ANCA

Churg-Strauss syndrome,
Kawasaki syndrome,
Giant-cell arteritis,
glomerular membrane basement disease,
rapidly progressive glomerulonephritis,
polyarteritis nodosa,
inflammatory bowel disease including Crohn’s disease,
primary sclerosing cholangitis,
rheumatoid arthritis, and
drug-induced vasculitis.

About 17 percent of patients with rheumatoid arthritis, especially juvenile arthritis, show the presence of P-ANCA.

Atypical P-ANCA

Primary sclerosing cholangitis
Autoimmune hepatitis

C-ANCA

Microscopic polyarteritis,
Wegener granulomatosis,
Henoch-Schonlein purpura,
Churg-Strauss syndrome,
Kawasaki syndrome,
Polyarteritis nodosa,
Glomerular basement membrane disease.

C-ANCA are seen in up to 85 percent of patients with Wegener granulomatosis and vasculitis, and levels or titers of C-ANCA tend to parallel disease activity.

PR-3 and MPO Reactivity
Some types of ANCA show reactivity with the proteins PR-3 and myeloperoxidase (MPO) and tests that demonstrate this reactivity should be used on all patients that test positive for C-ANCA or P-ANCA to help with disease diagnosis.

[ayaskant12]

that was a really exhaustive answer
thank u so much!

[ayaskant12]

NEW LIVER CLASSIFICATION
OKUDA

[mikerickin]

I have recently join this site and this is nice idea for providing us information about harrison. Would you mind to let us know more about this? Thanks!